Divider
Content Divider

Florida Keys Commercial Real Estate for Sale in the Florida Keys

Commercial real estate in the Florida Keys is available everywhere from Key Largo to Key West.  These great pieces of property can include anything from a business to a store front to an office building for sale in the Keys.  For those living in or looking to relocate to the Florida Keys commercial real estate can provide a fantastic business opportunity in a community that thrives on tourism and industry.  Possibilities can include things such as restaurants, stores, and other small businesses.  For a complete set of Florida Keys MLS commercial listings, browse here.

Total Listings 109
Order By:

$2,500
Rockland Key
Calle Uno   - MM: 9.00
Bed, Baths, SqFt Days Listed: 1070
Industrial - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

$17,600
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 1,650 SqFt Days Listed: 1478
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

$23,500
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 3,215 SqFt Days Listed: 1674
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

$40,000
Key West
Old Town Unrecord   - MM: 1.00
Bed, Baths, 8,396 SqFt Days Listed: 1879
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

$150,000
Key Largo
Dressings Add Tavernier   - MM: 91.50
Bed, Baths, 1,445 SqFt Days Listed: 546
Commercial - Contingent - Waterfront Yes
Side of Island: Bay/Gulf - n/a

Dont miss out on the opportunity to own a fully equipped restaurant nestled in the heart of Tavernier in the busy Tavernier Towne Shopping Center with Winn Dixie, Family Dollar, Post Office, Movie Theater and many more stores. Highly visible location with plenty of parking. This Turn Key restaurant is just waiting for a new owner. Build out is completely done and the restaurant equipment which is included is in pristine condition. The restaurant consists of 1445 sqft inside and a huge 680 sqft deck in the rear. You can add extra seating relax and unwind enjoying the views of the Florida Keys while listening to live music. Currently open for Breakfast and Lunch with room to grow. Complete packet with Financials are available to qualified buyers with a signed Confidential and Non-Disclosure Agreement. Business Only No Real Estate!

$155,000
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 367 SqFt Days Listed: 196
-16.22% ($30,000) 4 Price Changes : Last Change 2 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Very spacious office with skylight, located above the Courthouse Deli. Located in Old Town Key West just at the entrance of Truman Annex at the corner of Whitehead and Southard Street across from the Courthouse. The 367 Sq.ft. office is on the 3rd floor and building provides shared kitchenette and restrooms.

$195,000
Key Largo
Lake Surprise Properties   - MM: 106.00
Bed, Baths, 2,400 SqFt Days Listed: 119
Commercial - Active - Waterfront Yes
Side of Island: Bay/Gulf - n/a

2400 square feet ground floor currently leased to Deerfiled Trailer who sells, services and repairs trailers and other marine equiptment. Tenant has approximately 1000 square feet of unused space that can be sublet to another business. Building has Central Air.

$237,700
Key West
Key West Prof Plaza   - MM: 2.00
Bed, Baths, 2,337 SqFt Days Listed: 1067
-58.66% ($337,300) 4 Price Changes : Last Change 303 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Unique opportunity to own a office condo located on the 4th floor of the Kennedy Center. Unit 400 approximately 2337sq.ft., with an oversized top floor terrace overlooking Key Wests New Town area & canopy, shared with unit 402. Unit 400 is Bank Owned and is divided into 5 private offices w/ large bull-pen area, reception, storage, and kitchenette. Shared restroom facilities on each floor, also included in monthly condo dues: water, electric, bldg. maint. & insurance.

$310,000
Marathon
First Professional   - MM: 50.00
Bed, Baths, 947 SqFt Days Listed: 167
Commercial - Active - Waterfront No
Side of Island: Ocean - n/a

GREAT OPPORTUNITY TO OWN WELL ESTABLISHED BEAUTY SALON OR SPACE TO SUIT BUYERS NEEDS. PROFESSIONAL OFFICES ONLY ALLOWED BY CONDO RULES. Great Location near major shopping hub in Marathon. Currently set up for 3-4 hair stylists, 2 private rooms for massage or esthetician, and room for manicurists. There is a laundry closet including washer and dryer, a stock room and unisex restroom.

$329,000
Key West
New Town Unrecord   - MM: 3.00
1 Bed, 1 Baths, 1,475 SqFt Days Listed: 1112
-17.54% ($70,000) 2 Price Changes : Last Change 720 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Office Condo for Sale, centrally located in New Town on the 3rd floor of the Kennedy Center. This Professional Building caters to a diversity of innovative businesses and entrepreneurs in a friendly business environment. Unit 303 is approximately 1475sq.ft. with 6 private offices, large conference room, oversized waiting room/ workspace, and kitchenette. This building offers adequate off-street parking, elevators, and public restrooms on each floor. Included in the monthly Assoc Dues: water, electric, building maint, building insurance.

$349,000
Key West
New Town Unrecord   - MM: 3.00
Bed, Baths, 2,058 SqFt Days Listed: 1112
-36.08% ($197,000) 3 Price Changes : Last Change 603 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Office Condo for Sale, centrally located in New Town on the 3rd floor of the Kennedy Center. This Professional Building caters to a diversity of innovative businesses and entrepreneurs in a friendly business environment. Unit 307/305B is approximately 2058sq.ft. with 2 entrances, open floor plan with many workspace options, kitchenette, full bathroom, waiting area, private balcony. This building offers adequate off-street parking, elevators, and public restrooms on each floor. Included in the monthly Assoc Dues: water, electric, building maint, building insurance.

$359,000
Key West
Duval Sq Ph 1 & 2   - MM: 1.00
Bed, Baths, 577 SqFt Days Listed: 115
-28.06% ($140,000) 2 Price Changes : Last Change 2 Days Ago
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

This clean commercial space is ready for immediate use, perfect for either owner occupancy or rental investment. Located in the vibrant Duval Square complex, located in the heart of Key Wests commercial corridor., surrounded by an array of shops, restaurants, galleries, and offices. The unit comes with a covered parking space, with ample parking available for customers.

$419,000
Key West
Old Town Unrecord   - MM: 0.00
Bed, Baths, SqFt Days Listed: 283
-4.77% ($21,000) 1 Price Change : Last Change 62 Days Ago
Misc Prop Rig - Contingent - Waterfront No
Side of Island: Median - n/a

Very Rare license, 1 Transient/ROGO for an approved receiver site on Key West Island, 2 bedrooms, comes with 1 ROGO. Buy it while it lasts. Buyer should verify transferability.

$475,000
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, 718 SqFt Days Listed: 28
Commercial - Active - Waterfront No
Side of Island: Median - n/a

Seize this rare opportunity to own a prime commercial condo in the heart of Old Town Key West. Situated on bustling Truman Avenue, this vibrant space is ideal for establishing your business amongst a thriving mix of shops, restaurants, and historic landmarks. The condo boasts modern updates, including new flooring, fresh paint, and a renovated bathroom, providing a turnkey solution for your business needs. Embrace the island lifestyle and capitalize on the endless foot traffic - schedule your private viewing today!**HOA: $576/mo. includes building maintenance, insurance, and common area maintenance.

$479,000
Marathon
Gulfside Village   - MM: 50.00
1 Bed, 1 Baths, 1,421 SqFt Days Listed: 6
Commercial - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

Come see this beautiful office that has been completely renovated recently. With over 1,400 sq feet of office, this would make a great Dr. Office, Real Estate, Exc.Seller will consider leasing property out!!

$489,999
Key West
Old Town Unlisted   - MM: 1.00
Bed, Baths, SqFt Days Listed: 145
Commercial - Active - Waterfront No
Side of Island: Median - n/a

Presenting Key Wests Iconic Restaurant The Cafe for sale. This restaurant opportunity offers the only Vegan, Vegetarian, and Pescatarian food in Old Town Key West. This once in a lifetime Opportunity to continue this Key West Tradition can be yours today, contact listing Broker for more details.

$550,000
Key West
Old Town Unrecord   - MM: 1.00
Bed, Baths, SqFt Days Listed: 150
-21.43% ($150,000) 1 Price Change : Last Change 2 Days Ago
Commercial - Active - Waterfront No
Side of Island: Median - n/a

Rare opportunity to purchase a transient/ ROGO license. The Transient/ROGO license is coming from a 6 bedroom unit. Buyer to verify transferability.

$585,000
Marathon
Gulfside Village   - MM: 50.00
1 Bed, 1 Baths, 1,860 SqFt Days Listed: 311
Commercial - Active - Waterfront No
Side of Island: Bay/Gulf - n/a

Commercial Space Directly in the Middle of Gulfside Village. Triple Net Long Term Lease with existing Verizon Wireless tenants. Excellent Visibility! Excellent Rental History! Gulfside Village offers ample parking spaces, clean shopping center and friendly retail owners. Unit 21 has 1,860 sq feet of space, half bathroom and large storage/office area in the back of the store. Please DO NOT DISTURB the existing tenants/company.

$600,000
Summerland Key
Summerland Key Cove   - MM: 25.00
Bed, Baths, SqFt Days Listed: 374
Commercial - Active - Waterfront Yes
Side of Island: Ocean - n/a

COMMERCIAL CANAL FRONT VACANT LOT with 60 ft of Frontage on US 1 great opportunity for business great exposure, fenced lot with 60 ft dock ZONED SC, Bring your business to Paradise

$625,000
Key West
Duval Sq Ph 1 & 2   - MM: 1.00
Bed, Baths, 733 SqFt Days Listed: 90
Commercial - Active - Waterfront No
Side of Island: N/A - n/a

Join the exclusive Duval Square with this prime 733 sf. commercial unit. Walking distance to everything downtown on Duval St. Offering for sale at one of the lower prices per sq. ft. in the complex. This unit has been extensively renovated in the last two years including new AC, LPV flooring, new lighting, exam rooms, half bath and freshly painted. Unit has a nice open reception area with two private exam rooms. There is also a good size storage room in the rear. This space has a lot of natural light from 2 large plate glass windows and glass french doors in the front. This unit has good visibility with substantial frontage and a large sign above the entrance. Unit comes with 1 private parking space in the garage and ample parking for employees and customers in the front. Currently leased from Oct. 2022 to Sept. 30, 2025 total rent paid including base rent, cam and sales tax $3,317 per mos.The business, furniture and equipment seen in the photos are not included.

The information being provided by the Florida Keys MLS is exclusively for consumers' personal, non-commercial use, and it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The data is deemed reliable but is not guaranteed accurate by the MLS. Data last updated on 01-22-2025.
Back To TopMore Info
Terms / Privacy / Accessibility ADA